miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN)

Bacterial sepsis involves a complex interaction between the host immune response and bacterial LPS. LPS binds Toll-like receptor (TLR) 4, which leads to the release of proinflammatory cytokines that are essential for a potent innate immune response against pathogens. The innate immune system is tigh...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Kalantari, Parisa, Harandi, Omid F., Agarwal, Sarika, Rus, Florentina, Kurt-Jones, Evelyn A., Fitzgerald, Katherine A., Caffrey, Daniel R., Golenbock, Douglas T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392559/
https://ncbi.nlm.nih.gov/pubmed/28209713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749325
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