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The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure

SIRT1 (silent information regulator 2 homolog 1) is a crucial cellular survival protein especially in oxidative stress environments, and has been thought to locate within the nuclei, but also known to shuttle between cytoplasm and nuclei in some cell types. Here, we show for the first time the dynam...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yanagisawa, Satoru, Baker, Jonathan R., Vuppusetty, Chaitanya, Koga, Takeshi, Colley, Thomas, Fenwick, Peter, Donnelly, Louise E., Barnes, Peter J., Ito, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839577/
https://ncbi.nlm.nih.gov/pubmed/29509781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193921
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