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Role for reactive oxygen species in flow-stimulated inner medullary collecting duct endothelin-1 production

Inner medullary collecting duct (IMCD)-derived endothelin-1 (ET-1) is stimulated by volume expansion, in part through augmented luminal flow, whereupon it can elicit natriuresis and diuresis. Since flow can alter nitric oxide (NO) and reactive oxygen species (ROS), both of which can affect collectin...

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Detalles Bibliográficos
Publicado en:Am J Physiol Renal Physiol
Autores principales: Wheatley, Will, Kohan, Donald E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582894/
https://ncbi.nlm.nih.gov/pubmed/28515175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00103.2017
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