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Role for reactive oxygen species in flow-stimulated inner medullary collecting duct endothelin-1 production

Inner medullary collecting duct (IMCD)-derived endothelin-1 (ET-1) is stimulated by volume expansion, in part through augmented luminal flow, whereupon it can elicit natriuresis and diuresis. Since flow can alter nitric oxide (NO) and reactive oxygen species (ROS), both of which can affect collectin...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Wheatley, Will, Kohan, Donald E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582894/
https://ncbi.nlm.nih.gov/pubmed/28515175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00103.2017
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