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Flow regulation of endothelin-1 production in the inner medullary collecting duct
Collecting duct-derived endothelin (ET)-1 is an autocrine inhibitor of Na(+) and water reabsorption; its deficiency causes hypertension and water retention. Extracellular fluid volume expansion increases collecting duct ET-1, thereby promoting natriuresis and diuresis; however, how this coupling bet...
Enregistré dans:
| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360032/ https://ncbi.nlm.nih.gov/pubmed/25587122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00456.2014 |
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