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Osmolar regulation of endothelin-1 production by the inner medullary collecting duct

AIMS: Endothelin-1 (ET-1) is an autocrine inhibitor of collecting duct (CD) Na(+) and water reabsorption. CD ET-1 production is increased by a high salt diet and is important in promoting a natriuretic response. The mechanisms by which a high salt diet enhances CD ET-1 are being uncovered. In partic...

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Pubblicato in:Life Sci
Autori principali: Pandit, Meghana M., Gao, Yang, van Hoek, Alfred, Kohan, Donald E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861693/
https://ncbi.nlm.nih.gov/pubmed/26546722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2015.10.037
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