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Characterization of flow‐regulated cortical collecting duct endothelin‐1 production

Collecting duct (CD) endothelin‐1 (ET‐1) is an autocrine inhibitor of Na(+) and water reabsorption. Salt or water loading increases CD ET‐1 production; this is likely due, at least in part, to increased tubule fluid flow. The mechanisms by which flow stimulates CD ET‐1 production are incompletely un...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Ramkumar, Nirupama, Gao, Yang, Kohan, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328769/
https://ncbi.nlm.nih.gov/pubmed/28242818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13126
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