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Na delivery and ENaC mediate flow regulation of collecting duct endothelin-1 production

Collecting duct (CD) endothelin-1 (ET-1) is an important autocrine inhibitor of Na and water transport. CD ET-1 production is stimulated by extracellular fluid volume expansion and tubule fluid flow, suggesting a mechanism coupling CD Na delivery and ET-1 synthesis. A mouse cortical CD cell line, mp...

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Detalhes bibliográficos
Main Authors: Pandit, Meghana M., Strait, Kevin A., Matsuda, Toshio, Kohan, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362067/
https://ncbi.nlm.nih.gov/pubmed/22357920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00034.2012
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