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Role for reactive oxygen species in flow-stimulated inner medullary collecting duct endothelin-1 production

Inner medullary collecting duct (IMCD)-derived endothelin-1 (ET-1) is stimulated by volume expansion, in part through augmented luminal flow, whereupon it can elicit natriuresis and diuresis. Since flow can alter nitric oxide (NO) and reactive oxygen species (ROS), both of which can affect collectin...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Wheatley, Will, Kohan, Donald E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582894/
https://ncbi.nlm.nih.gov/pubmed/28515175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00103.2017
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