Lipid oxidation inactivates the anticoagulant function of protein Z-dependent protease inhibitor (ZPI)

Lipid oxidation due to oxidative stress plays an important role in the pathogenesis of inflammatory and thrombotic cardiovascular diseases. Several findings suggest that lipid peroxidation can alter the function of coagulation proteins and contribute to a hypercoagulable state, but the molecular mec...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Huang, Xin, Liu, Baoxin, Wei, Yidong, Beyea, Ryan, Yan, Han, Olson, Steven T.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582853/
https://ncbi.nlm.nih.gov/pubmed/28717005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.793901
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