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Exercise training prevents skeletal muscle plasma membrane cholesterol accumulation, cortical actin filament loss, and insulin resistance in C57BL/6J mice fed a western‐style high‐fat diet

Insulin action and glucose disposal are enhanced by exercise, yet the mechanisms involved remain imperfectly understood. While the causes of skeletal muscle insulin resistance also remain poorly understood, new evidence suggest excess plasma membrane (PM) cholesterol may contribute by damaging the c...

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Détails bibliographiques
Publié dans:Physiol Rep
Auteurs principaux: Ambery, Ashley G., Tackett, Lixuan, Penque, Brent A., Brozinick, Joseph T., Elmendorf, Jeffrey S.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582260/
https://ncbi.nlm.nih.gov/pubmed/28811359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13363
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