Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle

AIMS/HYPOTHESIS: Diminished cortical filamentous actin (F-actin) has been implicated in skeletal muscle insulin resistance, yet the mechanism(s) is unknown. Here we tested the hypothesis that changes in membrane cholesterol could be a causative factor, as organised F-actin structure emanates from ch...

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Bibliografische gegevens
Hoofdauteurs: Habegger, K. M., Penque, B. A., Sealls, W., Tackett, L., Bell, L. N., Blue, E. K., Gallagher, P. J., Sturek, M., Alloosh, M. A., Steinberg, H. O., Considine, R. V., Elmendorf, J. S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer-Verlag 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245823/
https://ncbi.nlm.nih.gov/pubmed/22002007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2334-y
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