Excess membrane cholesterol is an early contributing reversible aspect of skeletal muscle insulin resistance in C57BL/6NJ mice fed a Western-style high-fat diet

Skeletal muscle insulin resistance manifests shortly after high-fat feeding, yet mechanisms are not known. Here we set out to determine whether excess skeletal muscle membrane cholesterol and cytoskeletal derangement known to compromise glucose transporter (GLUT)4 regulation occurs early after high-...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Grice, Brian A., Barton, Kelly J., Covert, Jacob D., Kreilach, Alec M., Tackett, Lixuan, Brozinick, Joseph T., Elmendorf, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732462/
https://ncbi.nlm.nih.gov/pubmed/31237447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00396.2018
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