Excess membrane cholesterol is an early contributing reversible aspect of skeletal muscle insulin resistance in C57BL/6NJ mice fed a Western-style high-fat diet

Skeletal muscle insulin resistance manifests shortly after high-fat feeding, yet mechanisms are not known. Here we set out to determine whether excess skeletal muscle membrane cholesterol and cytoskeletal derangement known to compromise glucose transporter (GLUT)4 regulation occurs early after high-...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Endocrinol Metab
Asıl Yazarlar: Grice, Brian A., Barton, Kelly J., Covert, Jacob D., Kreilach, Alec M., Tackett, Lixuan, Brozinick, Joseph T., Elmendorf, Jeffrey S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732462/
https://ncbi.nlm.nih.gov/pubmed/31237447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00396.2018
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