Antidiabetogenic Effects of Chromium Mitigate Hyperinsulinemia-Induced Cellular Insulin Resistance via Correction of Plasma Membrane Cholesterol Imbalance

Previously, we found that a loss of plasma membrane (PM) phosphatidylinositol 4,5-bisphosphate (PIP(2))-regulated filamentous actin (F-actin) structure contributes to insulin-induced insulin resistance. Interestingly, we also demonstrated that chromium picolinate (CrPic), a dietary supplement though...

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Detalhes bibliográficos
Main Authors: Horvath, Emily M., Tackett, Lixuan, McCarthy, Alicia M., Raman, Priya, Brozinick, Joseph T., Elmendorf, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276473/
https://ncbi.nlm.nih.gov/pubmed/18165437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0410
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