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Direct NMR Evidence that Transient Tautomeric and Anionic States in dG•dT Form Watson-Crick like Base Pairs

The replicative and translational machinery utilizes the unique geometry of canonical G•C and A•T/U Watson-Crick base pairs to discriminate against DNA and RNA mismatches in order to ensure high fidelity replication, transcription, and translation. There is growing evidence that spontaneous errors o...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Szymanski, Eric S., Kimsey, Isaac J., Al-Hashimi, Hashim M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581979/
https://ncbi.nlm.nih.gov/pubmed/28290687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01156
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