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Dynamic Basis for dG•dT misincorporation via tautomerization and ionization
Tautomeric and anionic Watson-Crick-like mismatches play important roles in replication and translation errors through mechanisms that are not fully understood. Using NMR relaxation dispersion, we resolved a sequence-dependent kinetic network connecting G•T/U wobbles with three distinct Watson-Crick...
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Publicado no: | Nature |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808992/ https://ncbi.nlm.nih.gov/pubmed/29420478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25487 |
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