Dynamic Basis for dG•dT misincorporation via tautomerization and ionization

Tautomeric and anionic Watson-Crick-like mismatches play important roles in replication and translation errors through mechanisms that are not fully understood. Using NMR relaxation dispersion, we resolved a sequence-dependent kinetic network connecting G•T/U wobbles with three distinct Watson-Crick...

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Gepubliceerd in:Nature
Hoofdauteurs: Kimsey, Isaac J., Szymanski, Eric S., Zahurancik, Walter J., Shakya, Anisha, Xue, Yi, Chu, Chia-Chieh, Sathyamoorthy, Bharathwaj, Suo, Zucai, Al-Hashimi, Hashim M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808992/
https://ncbi.nlm.nih.gov/pubmed/29420478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25487
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