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Watson–Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation

RNA transcripts that include expanded CCUG repeats are associated with myotonic dystrophy type 2. Crystal structures of two CCUG-containing oligomers show that the RNA strands associate into slipped duplexes that contain noncanonical C–U pairs that have apparently undergone tautomeric transition or...

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Dettagli Bibliografici
Pubblicato in:RNA
Autori principali: Rypniewski, Wojciech, Banaszak, Katarzyna, Kuliński, Tadeusz, Kiliszek, Agnieszka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691832/
https://ncbi.nlm.nih.gov/pubmed/26543073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052399.115
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