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Multiscale Modeling of Wobble to Watson–Crick-Like Guanine–Uracil Tautomerization Pathways in RNA

Energetically unfavorable Watson–Crick (WC)-like tautomeric forms of nucleobases are known to introduce spontaneous mutations, and contribute to replication, transcription, and translation errors. Recent NMR relaxation dispersion techniques were able to show that wobble (w) G•U mispair exists in equ...

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Publicat a:Int J Mol Sci
Autors principals: Chandorkar, Shreya, Raghunathan, Shampa, Jaganade, Tanashree, Priyakumar, U. Deva
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196565/
https://ncbi.nlm.nih.gov/pubmed/34063755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115411
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