Fenfluramine Reduces [(11)C]Cimbi-36 Binding to the 5-HT(2A) Receptor in the Nonhuman Primate Brain

BACKGROUND: [(11)C]Cimbi-36 is a serotonin 2A receptor agonist positron emission tomography radioligand that has recently been examined in humans. The binding of agonist radioligand is expected to be more sensitive to endogenous neurotransmitter concentrations than antagonist radioligands. In the cu...

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Vydáno v:Int J Neuropsychopharmacol
Hlavní autoři: Yang, Kai-Chun, Stepanov, Vladimir, Martinsson, Stefan, Ettrup, Anders, Takano, Akihiro, Knudsen, Gitte M, Halldin, Christer, Farde, Lars, Finnema, Sjoerd J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Regular Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581490/
https://ncbi.nlm.nih.gov/pubmed/28911007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx051
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