Fenfluramine Reduces [(11)C]Cimbi-36 Binding to the 5-HT(2A) Receptor in the Nonhuman Primate Brain

BACKGROUND: [(11)C]Cimbi-36 is a serotonin 2A receptor agonist positron emission tomography radioligand that has recently been examined in humans. The binding of agonist radioligand is expected to be more sensitive to endogenous neurotransmitter concentrations than antagonist radioligands. In the cu...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Neuropsychopharmacol
Autori principali: Yang, Kai-Chun, Stepanov, Vladimir, Martinsson, Stefan, Ettrup, Anders, Takano, Akihiro, Knudsen, Gitte M, Halldin, Christer, Farde, Lars, Finnema, Sjoerd J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Regular Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581490/
https://ncbi.nlm.nih.gov/pubmed/28911007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx051
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