Genome-wide reconstruction of complex structural variants using read clouds

Microfluidic partitioning of long genomic DNA fragments, and barcoding of shorter fragments derived from them, retains long-range information in short sequencing reads. Such read cloud approaches represent a powerful and cost-effective alternative to single-molecule long-read sequencing. We develope...

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Vydáno v:Nat Methods
Hlavní autoři: Spies, Noah, Weng, Ziming, Bishara, Alex, McDaniel, Jennifer, Catoe, David, Zook, Justin M., Salit, Marc, West, Robert B., Batzoglou, Serafim, Sidow, Arend
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578891/
https://ncbi.nlm.nih.gov/pubmed/28714986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4366
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