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High-quality genome sequences of uncultured microbes by assembly of read clouds

Although shotgun metagenomic sequencing of microbiome samples enables partial reconstruction of the strain-level community structure, it remains difficult to obtain high-quality microbial genome drafts without isolation and culture. Here we present a novel application of read clouds, short read sequ...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Bishara, Alex, Moss, Eli L., Kolmogorov, Mikhail, Parada, Alma E., Weng, Ziming, Sidow, Arend, Dekas, Anne E., Batzoglou, Serafim, Bhatt, Ami S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465186/
https://ncbi.nlm.nih.gov/pubmed/30320765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4266
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