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Genome-wide reconstruction of complex structural variants using read clouds
Microfluidic partitioning of long genomic DNA fragments, and barcoding of shorter fragments derived from them, retains long-range information in short sequencing reads. Such read cloud approaches represent a powerful and cost-effective alternative to single-molecule long-read sequencing. We develope...
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| Pubblicato in: | Nat Methods |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578891/ https://ncbi.nlm.nih.gov/pubmed/28714986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4366 |
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