Dynamic change of transcription pausing through modulating NELF protein stability regulates granulocytic differentiation

The negative elongation factor (NELF) complex is a metazoan-specific factor essential for establishing transcription pausing. Although NELF has been implicated in cell-fate regulation, the cellular regulation of NELF and its intrinsic role in specific lineage differentiation remains largely unknown....

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Liu, Xiuli, Gogate, Aishwarya A., Tastemel, Melodi, Malladi, Venkat S., Yao, Huiyu, Nguyen, Kim, Huang, Lily Jun-Shen, Bai, Xiaoying
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Phagocytes, Granulocytes, and Myelopoiesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578628/
https://ncbi.nlm.nih.gov/pubmed/28868519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017008383
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