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Transcription Pausing Regulates Mouse Embryonic Stem Cell Differentiation
The pluripotency of embryonic stem cells (ESCs) relies on appropriate responsiveness to developmental cues. Promoter-proximal pausing of RNA polymerase II (Pol II) has been suggested to play a role in keeping genes poised for future activation. To identify the role of Pol II pausing in regulating ES...
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| Publicado no: | Stem Cell Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5732849/ https://ncbi.nlm.nih.gov/pubmed/29174978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2017.11.012 |
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