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Phosphorylation of histone H3.3 at serine 31 promotes p300 activity and enhancer acetylation
The histone variant H3.3 is enriched at enhancers and active genes, as well as repeat regions such as telomeres and retroelements, in mouse embryonic stem cells (mESCs)(1–3). While recent studies demonstrate a role for H3.3 and its chaperones in establishing heterochromatin at repeat regions(4–8), t...
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| Veröffentlicht in: | Nat Genet |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6598431/ https://ncbi.nlm.nih.gov/pubmed/31152160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0428-5 |
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