Dynamic change of transcription pausing through modulating NELF protein stability regulates granulocytic differentiation

The negative elongation factor (NELF) complex is a metazoan-specific factor essential for establishing transcription pausing. Although NELF has been implicated in cell-fate regulation, the cellular regulation of NELF and its intrinsic role in specific lineage differentiation remains largely unknown....

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Detalles Bibliográficos
Publicado en:Blood Adv
Main Authors: Liu, Xiuli, Gogate, Aishwarya A., Tastemel, Melodi, Malladi, Venkat S., Yao, Huiyu, Nguyen, Kim, Huang, Lily Jun-Shen, Bai, Xiaoying
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2017
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578628/
https://ncbi.nlm.nih.gov/pubmed/28868519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017008383
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