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Bcl6 Promotes Follicular Helper T Cell Differentiation and PD-1 Expression in a Blimp1-independent Manner
The transcription factors Bcl6 and Blimp1 have opposing roles in the development of the follicular helper T (T(FH)) cells: Bcl6 promotes and Blimp1 inhibits T(FH) cell differentiation. Similarly, Bcl6 activates, while Blimp1 represses, expression of the T(FH) cell marker PD-1. However, Bcl6 and Blim...
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| Опубликовано в: : | Eur J Immunol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578616/ https://ncbi.nlm.nih.gov/pubmed/28586108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747034 |
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