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Roles of T follicular helper cells and T follicular regulatory cells in Autoantibody Production in IL-2-deficient mice

Auto-antibodies (autoAbs) can result from excessive T follicular helper (Tfh) cell activity, while (Tfr) cells negatively regulate autoAb production. Interleukin-2 knockout (IL-2 KO) mice on the BALB/c background have elevated Tfh responses, produce autoAbs and develop lethal autoimmunity. We analyz...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunohorizons
Egile Nagusiak: Xie, Markus M., Liu, Hong, Corn, Caleb, Koh, Byung-Hee, Kaplan, Mark H., Turner, Matthew J., Dent, Alexander L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144868/
https://ncbi.nlm.nih.gov/pubmed/31356160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1900034
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