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Roles of T follicular helper cells and T follicular regulatory cells in Autoantibody Production in IL-2-deficient mice
Auto-antibodies (autoAbs) can result from excessive T follicular helper (Tfh) cell activity, while (Tfr) cells negatively regulate autoAb production. Interleukin-2 knockout (IL-2 KO) mice on the BALB/c background have elevated Tfh responses, produce autoAbs and develop lethal autoimmunity. We analyz...
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| Veröffentlicht in: | Immunohorizons |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144868/ https://ncbi.nlm.nih.gov/pubmed/31356160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1900034 |
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