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Follicular regulatory T cells inhibit the development of granzyme B–expressing follicular helper T cells

T follicular regulatory (TFR) cells are found in the germinal center (GC) response and help shape the antibody (Ab) response. However, the precise role of TFR cells in the GC is controversial. Here, we addressed TFR cell function using mice with impaired TFR cell development (Bcl6-flox/Foxp3-cre, or...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Xie, Markus M., Fang, Shuyi, Chen, Qiang, Liu, Hong, Wan, Jun, Dent, Alexander L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777838/
https://ncbi.nlm.nih.gov/pubmed/31434804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128076
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