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Follicular regulatory T cells inhibit the development of granzyme B–expressing follicular helper T cells

T follicular regulatory (TFR) cells are found in the germinal center (GC) response and help shape the antibody (Ab) response. However, the precise role of TFR cells in the GC is controversial. Here, we addressed TFR cell function using mice with impaired TFR cell development (Bcl6-flox/Foxp3-cre, or...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Xie, Markus M., Fang, Shuyi, Chen, Qiang, Liu, Hong, Wan, Jun, Dent, Alexander L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777838/
https://ncbi.nlm.nih.gov/pubmed/31434804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128076
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