T follicular regulatory cells and IL-10 promote food antigen–specific IgE

Food allergies are a major clinical problem and are driven by IgE antibodies (Abs) specific for food antigens (Ags). T follicular regulatory (Tfr) cells are a specialized subset of FOXP3(+) T cells that modulate Ab responses. Here, we analyzed the role of Tfr cells in regulating Ag-specific IgE usin...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Xie, Markus M., Chen, Qiang, Liu, Hong, Yang, Kai, Koh, Byunghee, Wu, Hao, Maleki, Soheila J., Hurlburt, Barry K., Cook-Mills, Joan, Kaplan, Mark H., Dent, Alexander L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324176/
https://ncbi.nlm.nih.gov/pubmed/32255767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132249
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