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Insights into the Role of Bcl6 in Follicular Helper T Cells Using a New Conditional Mutant Mouse Model

The transcriptional repressor Bcl6 controls development of the follicular helper T cell (T(FH)) lineage, however the precise mechanisms by which Bcl6 regulates this process are unclear. A model has been proposed whereby Bcl6 represses the differentiation of T cells into alternative effector lineages...

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Detalhes bibliográficos
Main Authors: Hollister, Kristin, Kusam, Saritha, Wu, Hao, Clegg, Ninah, Mondal, Arpita, Sawant, Deepali V., Dent, Alexander L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783642/
https://ncbi.nlm.nih.gov/pubmed/23980208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300378
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