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The role of follicular helper T cells and the germinal center in HIV-1 gp120 DNA prime and gp120 protein boost vaccination

The importance of follicular T helper (TFH) cells and the germinal center (GC) reaction in the humoral immune response has become clear in recent years, however the role of TFH cells and the GC in an HIV vaccine strategy remains unclear. In this study, we primed mice with gp120-encoding DNA and boos...

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Bibliografiske detaljer
Main Authors: Hollister, Kristin, Chen, Yuxin, Wang, Shixia, Wu, Hao, Mondal, Arpita, Clegg, Ninah, Lu, Shan, Dent, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186047/
https://ncbi.nlm.nih.gov/pubmed/25424808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.28659
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