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Reconstitution of beta-adrenergic receptor with components of adenylate cyclase.

Beta 1-Adrenergic receptor proteins were extracted from turkey erythrocyte membranes with lauroyl sucrose and digitonin and purified by affinity chromatography on a column of alprenolol agarose Affi-gel 10 or 15. The 5000-fold purified receptor is able to couple functionally with the stimulatory GTP...

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Publicat a:EMBO J
Autors principals: Hekman, M, Feder, D, Keenan, A K, Gal, A, Klein, H W, Pfeuffer, T, Levitzki, A, Helmreich, E J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6098472/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb02301.x
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