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Influence of the beta-adrenergic receptor concentration on functional coupling to the adenylate cyclase system.

Only part of the beta-adrenergic receptors can undergo functional coupling to the adenylate cyclase regulatory unit. This receptor subpopulation shows an increased affinity for agonists in the presence of Mg2+ and undergoes rapid "inactivation" (locking-in of the agonist) by the alkylating...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Severne, Y, Coppens, D, Bottari, S, Riviere, M, Kram, R, Vauquelin, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1984
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6087337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.15.4637
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