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Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.

The fate of the guanyl nucleotide bound to the regulatory site of adenylate cyclase was studied on a preparation of turkey erythrocyte membranes that was incubated with [3H]GTP plus isoproterenol and subsequently washed to remove hormone and free guanyl nucleotide. Further incubation of this prepara...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Cassel, D, Selinger, Z
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/212737/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.9.4155
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