Single-Construct Polycistronic Doxycycline-Inducible Vectors Improve Direct Cardiac Reprogramming and Can Be Used to Identify the Critical Timing of Transgene Expression

Direct reprogramming is a promising approach in regenerative medicine. Overexpression of the cardiac transcription factors Gata4, Mef2c, and Tbx5 (GMT) or GMT plus Hand2 (GHMT) directly reprogram fibroblasts into cardiomyocyte-like cells (iCMs). However, the critical timing of transgene expression a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Umei, Tomohiko C., Yamakawa, Hiroyuki, Muraoka, Naoto, Sadahiro, Taketaro, Isomi, Mari, Haginiwa, Sho, Kojima, Hidenori, Kurotsu, Shota, Tamura, Fumiya, Osakabe, Rina, Tani, Hidenori, Nara, Kaori, Miyoshi, Hiroyuki, Fukuda, Keiichi, Ieda, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578192/
https://ncbi.nlm.nih.gov/pubmed/28825623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081805
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados