Soft Matrix Promotes Cardiac Reprogramming via Inhibition of YAP/TAZ and Suppression of Fibroblast Signatures

Direct cardiac reprogramming holds great potential for regenerative medicine. However, it remains inefficient, and induced cardiomyocytes (iCMs) generated in vitro are less mature than those in vivo, suggesting that undefined extrinsic factors may regulate cardiac reprogramming. Previous in vitro st...

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Bibliografiset tiedot
Julkaisussa:Stem Cell Reports
Päätekijät: Kurotsu, Shota, Sadahiro, Taketaro, Fujita, Ryo, Tani, Hidenori, Yamakawa, Hiroyuki, Tamura, Fumiya, Isomi, Mari, Kojima, Hidenori, Yamada, Yu, Abe, Yuto, Murakata, Yoshiko, Akiyama, Tatsuya, Muraoka, Naoto, Harada, Ichiro, Suzuki, Takeshi, Fukuda, Keiichi, Ieda, Masaki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486305/
https://ncbi.nlm.nih.gov/pubmed/32857980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.07.022
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