Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions

Fibroblasts can be directly reprogrammed into cardiomyocyte-like cells (iCMs) by overexpression of cardiac transcription factors, including Gata4, Mef2c, and Tbx5; however, this process is inefficient under serum-based culture conditions, in which conversion of partially reprogrammed cells into full...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Yamakawa, Hiroyuki, Muraoka, Naoto, Miyamoto, Kazutaka, Sadahiro, Taketaro, Isomi, Mari, Haginiwa, Sho, Kojima, Hidenori, Umei, Tomohiko, Akiyama, Mizuha, Kuishi, Yuki, Kurokawa, Junko, Furukawa, Tetsushi, Fukuda, Keiichi, Ieda, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682292/
https://ncbi.nlm.nih.gov/pubmed/26626177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.10.019
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