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The hydrolytic susceptibility of prochelator BSIH in aqueous solutions
The prochelator BSIH ((E)-N′-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylidene)isonicotinohydrazide) contains a boronate group that prevents metal coordination until reaction with peroxide releases the iron chelator SIH ((E)-N′-(2-hydroxybenzylidene)isonicotinohydrazide). BSIH exists in aq...
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| Udgivet i: | Bioorg Med Chem Lett |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577934/ https://ncbi.nlm.nih.gov/pubmed/28734582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.07.019 |
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