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Iron Prochelator BSIH Protects Retinal Pigment Epithelial Cells against Cell Death Induced by Hydrogen Peroxide

Dysregulation of localized iron homeostasis is implicated in several degenerative diseases, including Parkinson’s, Alzheimer’s, and age-related macular degeneration, wherein iron-mediated oxidative stress is hypothesized to contribute to cell death. Inhibiting toxic iron without altering normal meta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Charkoudian, Louise K., Dentchev, Tzvete, Lukinova, Nina, Wolkow, Natalie, Dunaief, Joshua L., Franz, Katherine J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662444/
https://ncbi.nlm.nih.gov/pubmed/18835041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2008.08.001
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