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Iron Chelation Protects the Retinal Pigment Epithelial Cell Line ARPE-19 against Cell Death Triggered by Diverse Stimuli

PURPOSE: Cell death can be induced by exogenous reactive oxygen species (ROS). Endogenous ROS can also play a role in cell death triggered by agents that are not themselves ROS. One of the most potent ROS-generating systems is the iron-catalyzed Fenton reaction. Herein, the authors tested whether ir...

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Detalhes bibliográficos
Main Authors: Lukinova, Nina, Iacovelli, Jared, Dentchev, Tzvete, Wolkow, Natalie, Hunter, Allan, Amado, Defne, Ying, Gui-Shuang, Sparrow, Janet R., Dunaief, Joshua L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665187/
https://ncbi.nlm.nih.gov/pubmed/19182262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2545
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