The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse Mechanisms

PURPOSE: To investigate the effect of the iron chelator deferiprone (DFP) on sodium iodate (NaIO(3))–induced retinal degeneration and on the hereditary retinal degeneration caused by the rd6 mutation. METHODS: Retinas from NaIO(3)-treated C57BL/6J mice, with or without DFP cotreatment, were analyzed...

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Detalhes bibliográficos
Main Authors: Hadziahmetovic, Majda, Pajic, Miroslav, Grieco, Steven, Song, Ying, Song, Delu, Li, Yafeng, Cwanger, Alyssa, Iacovelli, Jared, Chu, Sally, Ying, Gui-shuang, Connelly, John, Spino, Michael, Dunaief, Joshua L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763881/
https://ncbi.nlm.nih.gov/pubmed/24049707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.1.2.7
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