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The Oral Iron Chelator Deferiprone Protects against Iron Overload–Induced Retinal Degeneration
PURPOSE. Iron-induced oxidative stress may exacerbate age-related macular degeneration (AMD). Ceruloplasmin/Hephaestin double-knockout (DKO) mice with age-dependent retinal iron accumulation and some features of AMD were used to test retinal protection by the oral iron chelator deferiprone (DFP). ME...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183363/ https://ncbi.nlm.nih.gov/pubmed/21051716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6207 |
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