Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone

Brain iron accumulates in several neurodegenerative diseases and can cause oxidative damage, but mechanisms of brain iron homeostasis are incompletely understood. Patients with mutations in the cellular iron-exporting ferroxidase ceruloplasmin (Cp) have brain iron accumulation causing neurodegenerat...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Zhao, Liangliang, Hadziahmetovic, Majda, Wang, Chenguang, Xu, Xueying, Song, Ying, Jinnah, H.A., Wodzinska, Jolanta, Iacovelli, Jared, Wolkow, Natalie, Krajacic, Predrag, Weissberger, Alyssa Cwanger, Connelly, John, Spino, Michael, Lee, Michael K., Connor, James, Giasson, Benoit, Harris, Z. Leah, Dunaief, Joshua L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943332/
https://ncbi.nlm.nih.gov/pubmed/26303407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13292
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