Ferroxidase Hephaestin's Cell-Autonomous Role in the Retinal Pigment Epithelium

Hephaestin (Heph) is a ferroxidase protein that converts ferrous to ferric iron to facilitate cellular iron export by ferroportin. Many tissues express either Heph or its homologue, ceruloplasmin (Cp), but the retina expresses both. In mice, a combined systemic mutation of Heph and systemic knockout...

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Autori principali: Wolkow, Natalie, Song, Delu, Song, Ying, Chu, Sally, Hadziahmetovic, Majda, Lee, Jennifer C., Iacovelli, Jared, Grieco, Steven, Dunaief, Joshua L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2012
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349827/
https://ncbi.nlm.nih.gov/pubmed/22342521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.12.041
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