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The hydrolytic susceptibility of prochelator BSIH in aqueous solutions

The prochelator BSIH ((E)-N′-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylidene)isonicotinohydrazide) contains a boronate group that prevents metal coordination until reaction with peroxide releases the iron chelator SIH ((E)-N′-(2-hydroxybenzylidene)isonicotinohydrazide). BSIH exists in aq...

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Bibliografski detalji
Izdano u:Bioorg Med Chem Lett
Glavni autori: Wang, Qin, Franz, Katherine J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577934/
https://ncbi.nlm.nih.gov/pubmed/28734582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.07.019
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