Učitavanje...
Collagen Complexity Spatially Defines Microregions of Total Tissue Pressure in Pancreatic Cancer
The poor efficacy of systemic cancer therapeutics in pancreatic ductal adenocarcinoma (PDAC) is partly attributed to deposition of collagen and hyaluronan, leading to interstitial hypertension collapsing blood and lymphatic vessels, limiting drug delivery. The intrinsic micro-regional interactions...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577321/ https://ncbi.nlm.nih.gov/pubmed/28855644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10671-w |
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