Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagendensity with interstitial pressure

Nanoparticle delivery into solid tumors is affected by vessel density, interstitial fluid pressure (IFP) and collagen, as shown here by contrasting the in vivo macroscopic quantitative uptake of 40 nm fluorescent beads in three tumor types. The fluorescence uptake was quantified on individual animal...

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Hlavní autoři: Torosean, Sason, Flynn, Brendan, Axelsson, Johan, Gunn, Jason, Samkoe, Kimberley S., Hasan, Tayyaba, Doyley, Marvin M., Pogue, Brian W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505807/
https://ncbi.nlm.nih.gov/pubmed/22841910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2012.07.002
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